Tuesday, October 4, 2022


Biotechnology News Magazine

Burns & Levinson Closes $4.2 Million Seed Financing for Anodyne Nanotech

Latest Posts

City of Hope to Accelerate Immunotherapy Research & Treatment Innovation with $15 Mil Gift from Ted Schwartz Family

Ted Schwartz, who is now cancer free, achieved complete remission at City of Hope in 2020 with the center's leading CAR T cell therapy after a 16-year battle with lymphoma, provided the gift to City of Hope to advance treatment options that offer better outcomes and quality of life for people living with cancer.

Neurocrine Biosciences Appoints Dr Ingrid Delaet as Chief Regulatory Officer

Prior to joining Neurocrine Biosciences, Dr Ingrid Delaet served as Senior Vice President, Regulatory Affairs at Intercept Pharmaceuticals, which she joined in 2016.

Astrea Bioseparations Introduces Nereus LentiHERO, a Fit-for-purpose Solution for Lentiviral Vector Purification

“We believe that AstreAdept will be a game-changer,” explained Astrea Bioseparations’ CEO Terry Pizzie. “Our approach was to rapidly develop and incorporate this material into the Nereus LentiHERO, a simple, fit-for-purpose device that radically transforms how lentivirus can be purified [in terms of speed, recovery, and efficiency].

At Pack Expo, Schreiner MediPharm to Debut Functional Labels Designed from More Sustainable Materials

Schreiner MediPharm advises he new label concepts are based on existing items in Schreiner MediPharm’s roster of functional labeling solutions.

Burns & Levinson has closed a $4.2 million seed investment from Velocity Partners, Relativity Healthcare Fund and Big Pi Ventures for Anodyne Nanotech, Inc., a Boston-based biotechnology company developing differentiated, transdermal forms of high-value drugs.

The investment will help expand the company’s Hero Patch™ platform, which uses microneedle technology to deliver clinically meaningful doses of macromolecules and small molecules. The deal, which closed on April 8, was led by Josef Volman, who co-chairs the firm’s Business Law Group, and Emmanuel Johnson.

This new class of microneedles was invented at Tufts University and is now the core technology of the Hero Patch™ platform at Anodyne, founded by Hojat Rezaei NejadKonstantinos Tzortzakis, and Jake Lombardo. By incorporating solvent-free bulk drug substance directly into microscopic porosities, Anodyne can load unprecedented amounts of the drug onto each microneedle. When the microneedle penetrates into the skin, the drug dissolves in the patient’s interstitial fluid and is systemically absorbed.

“Our set of technologies resolve many challenges that were hindering transdermal delivery of large molecules in a clinically relevant dosage for decades. Anodyne Nanotech’s primary focus is now on biologics, and we have shown delivery of monoclonal antibodies and peptides in vivo. I believe our technology is a gamechanger and unprecedented on many levels, and we continuously work to expand and develop our capabilities,” said Nejad, CTO of Anodyne Nanotech.

“We are proud to be working with Anodyne,” said Volman. “As a Tufts alumnus, it is particularly rewarding to be working with companies that have been launched out of Tufts with such a star team of former students. We look forward to working with Jake and Konstantinos and their impressive investor group on developing a strong business around their cutting-edge science.”

Not only does Anodyne’s technique allow for unprecedented drug loading, but also using the solid-state form of the drug substance can lead to improved stability. This promise would circumvent the need for cold-chain distribution, a critically important challenge for developing countries, with cost-saving advantages for the global biopharmaceutical industry. Anodyne has started collaborations with pharmaceutical companies to test particular biologics on the Hero Patch platform. The company plans to conduct clinical trials to characterize the bioequivalence, safety and tolerability of several Hero Patch products.

Latest Posts

Learn More




Our Sister Publication

Medical Device News Magazine