Friday, September 29, 2023


Biotechnology News Magazine

Burns & Levinson Closes $4.2 Million Seed Financing for Anodyne Nanotech

Latest Posts

Airway Therapeutics Completes Dose Escalation in Phase 1b Trial of Zelpultide Alfa (AT-100) for Very Preterm Infants at Risk for Bronchopulmonary Dysplasia

Airway Therapeutics began recruiting patients on March 28, 2023, for daily treatment up to 7 days at the highest dose of zelpultide alfa (rhSP-D) following a Data Safety Monitoring Committee (DSMC) report of no safety concerns.

Roche introduces navify® Algorithm Suite, a digital library of medical algorithms that enhances clinical decision-making to optimise patient care

At the global HIMSS1 Conference, Roche showcases navify Algorithm Suite, a single platform offering clinicians access to medical algorithms generating insights to help improve care decisions.

PathO3Gen Solutions UVZone® Proven 99.9993% Effective Against Candida Auris: Shoes and Floors in Healthcare Facilities Should Be Addressed as Outbreak Continues

PathO3Gen Solutions’ multi-patented UVZone Shoe Sanitizing Stations, when placed in high-traffic and high-risk areas, enhance healthcare facility infection control measures, and may improve overall hospital biosafety.

Pharming announces the first commercial shipments of Joenja® (leniolisib) to patients in the U.S.

Under the terms of Pharming's 2019 exclusive license agreement with Novartis for leniolisib, the corresponding first commercial sale of Joenja® triggers a $10 million milestone payment by Pharming to Novartis.

Burns & Levinson has closed a $4.2 million seed investment from Velocity Partners, Relativity Healthcare Fund and Big Pi Ventures for Anodyne Nanotech, Inc., a Boston-based biotechnology company developing differentiated, transdermal forms of high-value drugs.

The investment will help expand the company’s Hero Patch™ platform, which uses microneedle technology to deliver clinically meaningful doses of macromolecules and small molecules. The deal, which closed on April 8, was led by Josef Volman, who co-chairs the firm’s Business Law Group, and Emmanuel Johnson.

This new class of microneedles was invented at Tufts University and is now the core technology of the Hero Patch™ platform at Anodyne, founded by Hojat Rezaei NejadKonstantinos Tzortzakis, and Jake Lombardo. By incorporating solvent-free bulk drug substance directly into microscopic porosities, Anodyne can load unprecedented amounts of the drug onto each microneedle. When the microneedle penetrates into the skin, the drug dissolves in the patient’s interstitial fluid and is systemically absorbed.

“Our set of technologies resolve many challenges that were hindering transdermal delivery of large molecules in a clinically relevant dosage for decades. Anodyne Nanotech’s primary focus is now on biologics, and we have shown delivery of monoclonal antibodies and peptides in vivo. I believe our technology is a gamechanger and unprecedented on many levels, and we continuously work to expand and develop our capabilities,” said Nejad, CTO of Anodyne Nanotech.

“We are proud to be working with Anodyne,” said Volman. “As a Tufts alumnus, it is particularly rewarding to be working with companies that have been launched out of Tufts with such a star team of former students. We look forward to working with Jake and Konstantinos and their impressive investor group on developing a strong business around their cutting-edge science.”

Not only does Anodyne’s technique allow for unprecedented drug loading, but also using the solid-state form of the drug substance can lead to improved stability. This promise would circumvent the need for cold-chain distribution, a critically important challenge for developing countries, with cost-saving advantages for the global biopharmaceutical industry. Anodyne has started collaborations with pharmaceutical companies to test particular biologics on the Hero Patch platform. The company plans to conduct clinical trials to characterize the bioequivalence, safety and tolerability of several Hero Patch products.

Latest Posts

Learn More




Our Sister Publication

Medical Device News Magazine