Friday, September 30, 2022


Biotechnology News Magazine

Huili Biotechnology Completes Series A Financing Round with Hundreds of Million RMB

Co-led by Legend Capital

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This financing round was co-led by Legend Capital and the fresh capital will be used to accelerate the construction and operation of large-scale production facilities, the R&D of new product pipelines and the expansion of the talent team.

Founded in 2018, Huili Bio is dedicated to the computational design of enzyme components at the core of synthetic biological reactions. With cutting-edge achievements, Huili Bio is one of the few bio-manufacturing companies with comprehensive capabilities in core technology, mass production on a large scale and closed-loop commercialization. It provides solutions in multiple fields such as pharmaceutical intermediates, animal protection and food. In addition to an R&D center in Tianjin, Huili Bio has also established a production base in Taizhou City, Jiangsu Province, which is under the expansion of flexible production line.

Huili Bio’s enzyme computational design platform is the first computational platform in China to realize the full-scenario design of enzymes. This platform enables the company to transform products in the pharmaceutical field, so as to achieve high efficiency from laboratory development, industrial production to commercialization, reducing costs by nearly 30% and increasing yields by almost 70% compared to traditional chemical methods, and also helps Huili Bio deploy more than 10 innovative products in various fields.

Commenting on the financing, Henry JI, Executive Director of Legend Capital, said: “The synthetic biomaterials market is vast and an important area in the green and low-carbon direction. As the core component of synthetic biology, the design and transformation of enzymes will benefit more traditional biotechnology industries with low-cost and sustainable green production methods. Legend Capital has long focused on investment in the ‘IT+’ industry, and Huili Bio is a model of combining information technology and biotechnology (IT+BT). With a background in combining industry and research, Huili Bio is a company with differentiated product selection and multi-pipeline extension capabilities. The company has mastered the industry’s leading enzyme computing design technology and has rapidly achieved the scale production of high-value-added products such as pharmaceutical intermediates through the layout of the whole industry chain and has been fully recognized by the industry’s head customers. Legend Capital is glad to join hands with Huili Biotech to contribute to China’s biological ‘intelligence’.”

As an intersection of information science, life science and material science, synthetic biology and bio-based materials have been the focus of Legend Capital’s carbon-neutral technology investments. Under the background of carbon peaking and carbon neutrality, Legend Capital’s investments focus on energy decarbonization, vehicle electrification/intelligence, synthetic biology, etc. Energy decarbonization includes photovoltaic, wind power and smart grid; vehicle electrification/intelligence includes lithium battery vehicles, hydrogen fuel cell vehicles, battery recycling and others. Legend Capital has made investments in the field of synthetic biology by investing in outstanding companies such as Huili Bio, Zhongke Guosheng, and Tidetron Bio.

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