Thursday, August 11, 2022

561.316.3330

MultiOmic Health and Mesh Bio Partner to Use AI to Develop Precision Medicines & Diagnostics for Chronic Metabolic Disease

Latest Posts

New Study Highlights Superior Efficacy of At-home Dry EEG assessment Compared to Lab-based Monitoring

Results indicate that easy-to-use task-driven EEG can yield clinical-grade data in large-scale, real-world investigations in neuroscience with extremely high adherence rates.

Gamida Cell Announces Dosing of First Patient in Company-Sponsored Phase 1/2 Study of NK Cell Therapy Candidate GDA-201

“We are excited to further advance the development of GDA-201, a NAM-enabled natural killer (NK) cell therapy candidate which we believe has the potential to be a new readily available, cryopreserved treatment option for cancer patients with relapsed/refractory lymphoma,” said Ronit Simantov, M.D., chief medical and scientific officer of Gamida Cell.

Akadeum Life Sciences Announces New Dead Cell Removal Kit Using Microbubble Technology

Akadeum Life Sciences advises that the new buoyant separation method creates a more effective way for researchers to use valuable samples with a higher retention rate of viable cells than current magnetic techniques.

Bio-Rad Extends Range of StarBright Violet and UltraViolet Dyes for Multiplex Flow Cytometry

StarBright Violet 760, StarBright UltraViolet 575, and StarBright UltraViolet 605 dyes conjugated to highly validated antibodies for multicolor panel design in immunology research.

MultiOmic Health, an artificial intelligence (AI)-enabled drug discovery company, and Mesh Bio, a digital health startup transforming chronic disease management through predictive analytics, today announced their partnership to conduct an observational clinical study on patients with chronic metabolic disease and increased risk of complications such as chronic kidney disease.

MultiOmic Health advises the partnership will provide access to data from patient populations in Asia that have historically been underrepresented in chronic metabolic disease studies.

Mesh will collaborate with its network of healthcare provider customers to recruit patients for the study. MultiOmic Health will generate genomic, proteomic, metabolomic and potentially other omics data from anonymized body fluid samples. These will be combined with anonymized data from clinical and diagnostic tests for both companies to build a rich multi-omics dataset and derive AI-based computational biology models.

The study will enable MultiOmic Health and Mesh to progress their respective R&D programs to develop precision therapeutic and diagnostic products that will transform the lives of patients with metabolic syndrome-related conditions. They will also jointly conduct collaborative projects to enhance patient stratification for other biopharma and medtech companies’ clinical-stage R&D programs.

Metabolic syndrome-related conditions such as type 2 diabetes mellitus (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular disease (ASCVD), non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) arise from a common set of risk factors present in half the world’s adult population. These age-related conditions can lead to serious consequences, including heart attack, stroke, blindness, nerve damage, foot amputation, kidney dialysis and liver failure. Prior to the COVID-19 pandemic, they accounted for half the world’s deaths and nearly US$ 2 trillion in global healthcare spending1. This burden will be further exacerbated by the pandemic. A significant proportion of COVID-related hospitalizations and fatalities arose in patients with metabolic syndrome conditions2 and recent studies have indicated that COVID survivors have an increased risk of being diagnosed with T2D3 and CKD4.

“Longitudinal multi-omics data combined with deep clinical phenotyping is essential to developing transformative therapeutics and diagnostics in chronic multi-factorial diseases,” said Angeli Möller, PhD, Vice-Chairperson and co-founder of the Alliance for Artificial Intelligence in Healthcare, the global advocacy organization for applying AI solutions to improve patient lives. “In contrast to most of the historical research for these diseases that has relied on Caucasian patients, this partnership will generate new and much needed insights specific to populations in Asia.”

“Mesh Bio is committed to driving precision clinical interventions in the management of chronic metabolic disease, in order to improve patient outcomes. Our vision is for holistic patient assessment, powered by analytics on fullstack biology,” said Andrew Wu, PhD, Co-Founder and CEO of Mesh. “We are delighted to partner with MultiOmic Health on this important study for patients in Asia. Their therapeutic development programs for metabolic disease intervention have deep synergies with Mesh Bio’s mission to develop digital care delivery solutions for these diseases.”

“This partnership gives us access to a population base in Asia exhibiting high and increasing prevalence of metabolic syndrome-related conditions,” said Robert Thong, Co-Founder and CEO of MultiOmic Health. “We are delighted to collaborate with Mesh Bio as a like-minded and capable strategic partner working with healthcare providers that have many patients in our target chronic medical conditions. Our product development programs and technical teams also complement each other.”


References
References
1) MultiOmic Health estimates from aggregating published statistics for cardiovascular disease, type 2 diabetes, chronic kidney disease, non-alcoholic fatty liver disease and polycystic ovary syndrome.
2) Diabetes Care 2021;44(9):1916–1923
3) Article in Nature: https://www.nature.com/articles/d41586-022-00912-y
4) Article British Medical Journal: https://www.bmj.com/content/374/bmj.n2189

Latest Posts

Learn More

spot_img

Subscribe

spot_img

Our Sister Publication

Medical Device News Magazine