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R-Pharm Group and Koek Sign an Agreement to Commercialize Fertile Chips for In Vitro Fertilization

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April 19, 2021

R-Pharm Group and Koek, a Turkish biotechnological company, have announced signing an agreement to commercialize microfluidic chips Fertile® in the Russian Federation.

This cooperation will include seeking regulatory approval followed by the distribution of Fertile, Fertile Plus, and Fertile Ultimate devices for sperm preparation and selection of the best spermatozoa for in vitro fertilization (IVF).

According to the Russian Association of Human Reproduction (RAHR), in 2018 30,796 successful deliveries took place following the use of Assisted Reproductive Technologies (ART).

Meanwhile, only 1 out of 3 IVF cycles results in the birth of a new life. Fertile® devices are used to select spermatozoa from the native sperm, separating healthy and adequately mobile spermatozoa from damaged and poorly mobile ones. The chip contains a sieve with microchannels through which the most vigorous spermatozoa swim a Marathon distance of its kind to the outlet port where the most viable cells are accumulated.

The method prevents damaging spermatozoa by oxidative stress, thereby improving the quality of embryos and the efficiency of IVF cycles. This novel technology has a promising potential as it saves the time of sperm preparation prior to IVF, by using a simple albeit unique way of sorting spermatozoa, reduces cell exposure to oxidative damage during the procedure, and is quite convenient for embryologists working in a laboratory. All of this results in higher IVF efficiency and embryo survival rate.

Anastasia Batrak, R-Pharm Vice-President, Strategic marketing: “As of today, about a half of IVF cycles are reimbursed via compulsory health insurance, also covering assisted reproductive technologies. We expect the novel method of spermatozoa selection, based on the use of microfluidic Fertile® chips, will be recommended for endorsement by clinical guidelines on ART and will shortly become available to patients via compulsory health insurance.”

Selçuk Kılınç, KOEK Biotechnology, CEO: “We are delighted by the cooperation with such reputable company like R-Pharm. FERTILE has helped many couples around the world fulfilling their dream of having a baby. We are encouraged and proud being able to offer this solution to the Russian population together with our partner R-Pharm.”

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